Preview isawesome for anumber ofreasons, and writer Dave Winer points out that it also makes a great paint program.
Paintbrush is a simple paint program for Mac OS X, reminiscent of Microsoft Paint and Apple's own now-defunct MacPaint. It provides users with a means to make simple images quickly, something that has been noticeably absent from the Mac for years. Paint for Mac Pro is the best Mac version of paint program used to edit image, filters and paint on Mac. A good alternative to Paint Tool Sai Mac.
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While you can't create new works of art using just Preview, it is a more powerful editor than it looks at a glance. Just open up any image in Preview, click the toolbox icon, and you'll get a bunch of editing tools. You can easily make backgrounds transparent, annotate images, draw whatever you want as an image, and more. Preview doesn't have the charm of MS Paint, but it does a bit more than you'd think.
A hidden Mac paint program | Scripting News